APPETITE SUPPRESSANT Product Details and Refferences

Data Sheet:   APPETITE SUPPRESANT  – promotes weight loss and appetite control throughout the day ; written by Pharm. D. Neil Ross

APPETTIE SUPPRESANT capsules are formulated to help control appetite and help convert fat to energy. The following is a description of the ingredients and the uses in the formulation.

Hoodia Gordonii, for thousands of years, has been eaten by the Bushmen of South Africa to fight off hunger during their week long hunting trips. For the Bushmen there is no question as to the appetite suppressant power of Hoodia Gordonii – it is a simple fact of life – if you are going on a long journey you chew on hoodia to avoid hunger.

While the Bushmen did not do formal clinical studies, there are thousands of years of real world evidence that eating Hoodia works as an appetite suppressant. To the Bushmen eating hoodia to suppress appetite is as clear as drinking water to quench thirst.

So, for thousands of years the Bushmen have been eating Hoodia Gordonii to decrease appetite and increase energy. While the Bushmen knew all about the powers of Hoodia, it was not until the mid-60 that the first research was done on Hoodia as an appetite suppressant. Even then, it took another 30 years for South African laboratories to isolate the specific appetite suppressing ingredient in Hoodia. This ingredient was called P57 (or p-57). Because P57 from pure Hoodia gordonii suppresses appetite, finding the biochemical mechanism by which it acts on the brain would be important to future discoveries in obesity. Brown researchers conducted various experiments with normal, healthy rats as they injected small amounts of P57 from pure Hoodia gordonii extract directly into a small cavity in the third intracerebral ventricle their brain located above the hypothalamus, which lies deep in the forebrain. This is a primordial region of the brain, part of the limbic system that controls numerous drives and functions such as appetite, sex, sleep and mood. It seems that P57 up-regulates hypothalamic ATP (adenosine triphosphate — the energy compound) by as much as 100%. And it is those high concentrations of ATP that cause the hypothalamus to signal the brain to stop eating.

 

 

When the Brown researchers put animals on low-calorie diets, their hypothalamic ATP levels dropped precipitously. But the same animals, given P57 while eating a calorie-restricted diet, had normal hypothalamic ATP. Is this getting interesting? Hoodia may be the answer to the chronic hunger pangs of low-calorie dieting. By boosting ATP levels in the hypothalamus, P57 works just like calories (from sugar, starch, whatever), which also boost ATP levels in the hypothalamus. The obvious difference is that P57 has no calories. On a weight basis, P57 has been found 10,000 times more potent than sugar in suppressing appetite. In 2002, CSIR officially recognized the San tribespeople’s rights over hoodia, allowing them to take a percentage of the profits and any spin-offs resulting from the marketing of hoodia.^[5] H. Gordonii is a protected plant which may only be wild-harvested by individuals and the few companies which have been granted a license.^[6]

By December of 2001, and $20 million later, Phytopharm who was given the rights to the compound had the first clinical study that showed obese people who took P57 (extracted from Hoodia Gordonii) ate 1,000 calories fewer per day with no adverse side effects! Simply put, if you took P57, your desire to eat was extremely reduced. Phytopharm completed a double-blind, placebo-controlled clinical study in overweight, but otherwise healthy volunteers using the P57 extract from Hoodia gordonii. The participants were split into two groups, one group received the P57 and the other received a placebo. Both groups were told to continue their normal diet and exercise. The results were as follows:

When comparing the P57 group to the Placebo group:

• The P57 group had a statistically significant reduction in body fat
• The P57 group had a statistically significant reduction in caloric intake
• The P57 had no adverse side effects

 

 

 

As much as everyone argues about which is better low carb or low fat – in the end losing weight is a simple equation. Take in less calories than you burn and you will lose weight. It is really simple math, you cannot gain weight if you consume less calories than you burn. Hoodia gives you a powerful weapon to fight hunger and therefore take in less calories. No need to run the body hotter or faster or harder, simply you consume less calories and therefore lose weight. The Source of Hoodia in Eat Less is certified South African Hoodia, not adulterated which is the only source ever studied.

 

Green tea has been used for thousands of years and has many benefits. One of them is green tea’s thermo-genic properties. This means the green tea causes your metabolism to heat up, or consume fuel at a faster rate. The faster your metabolism, the more fuel it needs. We store fat as fuel for our body. Your metabolism, consuming fat at a faster rate, causes you to lose fat weight.

Green tea also creates the feeling of fullness, making it a very effective appetite suppressant. When your body is no longer constantly craving foods, you can concentrate on healthier eating habits.

A proponent in green tea called EGCG reduces the amount of lipids (fat) you absorb when you eat. This benefits your cholesterol level, causes weight loss and is very healthy for your heart.

Black tea, oolong tea, and green tea come from the same Camellia sinensis plant. But unlike the other two varieties, green tea leaves are not fermented before steaming and drying.

Continue reading below…

Most teas contain large amounts of polyphenols, which are plant-based substances that have been shown to have antioxidant, anticancer, and antiviral properties.

However, green tea is particularly rich in a type of polyphenols called catechins. These substances have also been shown to have anti-inflammatory and anticancer properties, but recent research in animals show that catechins may also affect body fat accumulation and cholesterol levels.

Researchers looked at the effects of catechins on body fat reduction and weight loss in a group of 35 Japanese men. The men had similar weights based on their BMI (body mass index, an indicator of body fat) and waist sizes.

The men were divided into two groups. For three months, the first group drank a bottle of oolong tea fortified with green tea extract containing 690 milligrams of catechins, and the other group drank a bottle of oolong tea with 22 milligrams of catechins.

During this time, the men consumed identical breakfasts and dinners and were instructed to control their calorie and fat intake at all times so that overall total diets were similar.

After three months, the study showed that the men who drank the green tea extract lost more weight (5.3 pounds vs. 2.9 pounds) and experienced a significantly greater decrease in BMI, waist size, and total body fat.

In addition, LDL “bad” cholesterol went down in the men who drank the green tea extract.

Researchers say the results indicate that catechins in green tea not only help burn calories and lower LDL cholesterol but may also be able to mildly reduce body fat.

 

 

Chromium is a mineral that humans require in trace amounts, although its mechanisms of action in the body and the amounts needed for optimal health are not well defined. It is found primarily in two forms: 1) trivalent (chromium 3+), which is biologically active and found in food.

This popular nutritional supplement is a combination of the element chromium and picolinic acid.  Chromium is a naturally-occurring mineral, trace amounts of which are found in everyday foods like meat, poultry, fish, and whole-grain breads.  When foods are processed, they are stripped of natural chromium, making American diets generally very low in chromium; studies estimate an average daily chromium consumption of 33 mcg.  In 1968, it was demonstrated that when animals do not receive adequate levels of chromium, insulin is not optimally effective, and damage to insulin-dependent systems can occur (Schroeder, 1968).  This led the FDA to recommend a daily chromium intake of approximately 130 mcg, as infinitesimal amounts of chromium are needed to aid the transport of blood glucose across cell membranes.

Chromium is known to enhance the action of insulin [1-3], a hormone critical to the metabolism and storage of carbohydrate, fat, and protein in the body [4]. In 1957, a compound in brewers’ yeast was found to prevent an age-related decline in the ability of rats to maintain normal levels of sugar (glucose) in their blood [3]. Chromium was identified as the active ingredient in this so-called “glucose tolerance factor” in 1959 [5].

Chromium also appears to be directly involved in carbohydrate, fat, and protein metabolism [1-2,6-11]. Chromium works by improving sensitivity to insulin, which in turn reduces appetite, energy dips and sugar and fat cravings, thereby helping weight loss. That’s the conclusion of a recent study published in the journal Diabetes Technology & Therapeutics. (1) Combining chromium with picolinic acid simply aids in efficient chromium absorption, and it is this combined form that is popular on the diet market today.

 

Thus, the APPETITE SUPPRESANT capsules are designed to help support weight control by appetite reduction, and fat conversion to energy.

 

 

 

REFERENCES

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Green Tea EGCG(Catechins)

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